High-Intensity Resistance Exercise and Schinus terenbinthifolius Supplementation Attenuate Oxidative Stress and Muscle Damage Biomarkers

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چکیده

High-intensity physical exercises can cause oxidative stress and muscle damage. Several medicinal plants have been used as antioxidant anti-inflammatory agents. The present study evaluated high-intensity resistance exercise (HIRE) associated with Schinus Terebentifholius ethanolic extract (EE) on parameters damage in Wistar rats. Animals were divided into 04 groups (n=10/group): 1. Control (CG) - animals that did not undergo HIRE treated vehicle (distilled water, orally); 2. Acute (AE) submitted to acute session; 3. Exercise + (EV) underwent 4. (EX) administered terebenthifolius EE (100mg/Kg, orally) the session. showed high vitro activity (13.88 ± 0.36 mg/mL). Before experimental period, lactate was measured at pre post moments of AE (p<0.0001) EX groups. After session, following evaluated: {malondialdehyde (MDA), sulfhydryl (SH) ferric reducing power (FRAP)}, (creatine kinase (CK) dehydrogenase (LDH)), alanine aminotransferase (ALT) aspartate (AST). In vivo analyses group compared EV groups, respectively: hepatic (MDA: p<0.0001 SH: p=0.0033, both; FRAP: p=0.0011 p=0.0047), (MDA, SH p<0.0001, CK: p=0.0001 p<0.0001; LDH: both), serum levels p=0.0003, p=0.0012, p=0.0056, p=0.0200, p=0.0017 p=0.0165) significant. There no significant difference ALT AST markers. It could be concluded attenuated

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ژورنال

عنوان ژورنال: International Journal of Morphology

سال: 2022

ISSN: ['0717-9502', '0717-9367']

DOI: https://doi.org/10.4067/s0717-95022022000300781